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Article

Emerging roles of a chemoattractant receptor GPR15 and ligands in pathophysiology

30 Jun 2023

Abstract excerpt

Chemokine receptors play a central role in the maintenance of immune homeostasis and development of inflammation by directing leukocyte migration to tissues. GPR15 is a G protein-coupled receptor (GPCR) that was initially known as a co-receptor for human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV), with structural similarity to other members of the chemoattractant receptor family. Since...

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PMID: 37457732
DOI: 10.3389/fimmu.2023.1179456

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