Molecular recognition of itch-associated neuropeptides by bombesin receptors

Abstract excerpt

Itch, especially persistent itch (or chronic pruritus) in patients with allergic skin diseases and/or neuropathic problems, significantly affects sleep, mood and individual health. Extensive efforts have been made to develop novel therapeutic strategies to fight itch. Unfortunately, there is no FDA-approved treatment for chronic pruritus despite great efforts in antipruritic research in the past few decades. 1

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