Article
A central role for R7bp in the regulation of itch sensation.
Pain - 1 May 2017
Pandey Mritunjay, Zhang Jian-Hua, Mishra Santosh K, Adikaram Poorni R, Harris Benjamin, Kahler John F, Loshakov Anna, Sholevar Roxanne, Genis Allison, Kittock Claire, Kabat Juraj, Ganesan Sundar, Neubig Richard R, Hoon Mark A, Simonds William F
Abstract excerpt
Itch is a protective sensation producing a desire to scratch. Pathologic itch can be a chronic symptom of illnesses such as uremia, cholestatic liver disease, neuropathies and dermatitis, however current therapeutic options are limited. Many types of cell surface receptors, including those present on cells in the skin, on sensory neurons and on neurons in the spinal cord, have been implicated in itch signaling....
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