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Genomic Signatures from Clinical Tumor Sequencing in Patients with Breast Cancer Having Germline BRCA1/2 Mutation.

Cancer research and treatment - 1 Jan 2023

Kim Ju Won, Kang Hyo Eun, Choi Jimi, Yun Seung Gyu, Jung Seung Pil, Bae Soo Yeon, You Ji Young, Choi Yoon-Ji, Kim Yeul Hong, Park Kyong Hwa

Abstract excerpt

PURPOSE: BRCA1 and BRCA2 are among the most important genes involved in DNA repair via homologous recombination (HR). Germline BRCA1/2 (gBRCA1/2)-related cancers have specific characteristics and treatment options but conducting gBRCA1/2 testing and interpreting the genetic imprint are sometimes complicated. Here, we describe the concordance of gBRCA1/2 derived from a panel of clinical tumor tissues using...

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Identifiers

PMID: 35681111
DOI: 10.4143/crt.2021.1567
PMCID: PMC9873314

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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