Article
Causal effects of psychosocial factors on chronic back pain: a bidirectional Mendelian randomisation study.
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society - 1 Jul 2022
Williams Frances M K, Elgaeva Elizaveta E, Freidin Maxim B, Zaytseva Olga O, Aulchenko Yurii S, Tsepilov Yakov A, Suri Pradeep
Abstract excerpt
PURPOSE: Risk factors for chronic back pain (CBP) may share underlying genetic factors, making them difficult to study using conventional methods. We conducted a bi-directional Mendelian randomisation (MR) study to examine the causal effects of risk factors (education, smoking, alcohol consumption, physical activity, sleep and depression) on CBP and the causal effect of CBP on the same risk factors. METHODS:...
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