Article
Genotype-by-environment interactions in chronic back pain.
The spine journal : official journal of the North American Spine Society - 1 Aug 2023
Kuznetsov Ivan A, Tsepilov Yakov A, Freidin Maxim B, Williams Frances M K, Suri Pradeep, Aulchenko Yurii S
Abstract excerpt
BACKGROUND CONTEXT: Chronic back pain (CBP) is a common debilitating condition with substantial societal impact. While understanding genotype-by-environment (GxE) interactions may be crucial to achieving the goals of personalized medicine, there are few large-scale studies investigating this topic for CBP. None of them systematically explore multiple CBP risk factors. PURPOSE: To estimate the extent to which...
Topics
- Humans
- Gene-Environment Interaction
- Case-Control Studies
- Prospective Studies
- Back Pain
- Genotype