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Article

Disentangling the relationship between depression and chronic widespread pain: A Mendelian randomisation study.

Seminars in arthritis and rheumatism - 1 Jun 2023

Zhao Sizheng Steven, Holmes Michael V, Alam Uazman

Abstract excerpt

OBJECTIVE: Depression and chronic widespread pain (CWP) frequently coexist, but whether depression is an independent causal risk factor for CWP, and/or vice versa, remains unclear. We investigated the bidirectional causal relationship between depression and CWP. METHODS: We performed a two-sample Mendelian randomisation (MR) study to estimate the causal relationship between genetically predicted depression...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36963129
DOI: 10.1016/j.semarthrit.2023.152188

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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