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Article

Causal impacts of smoking on pain conditions and the mediating pathways: a mendelian randomization study.

Scientific reports - 8 Oct 2024

Zhang Kai, Liang Hongjin

Abstract excerpt

Smoking is a risk factor for multiple diseases. We performed mendelian randomization (MR) analyses to investigate the causal association of smoking initiation on pain conditions and the potential mediating pathways. Genetic associated with smoking initiation at the genome-wide significance level were selected as instrumental variables. Genetic associations with 10 pain conditions were derived from the FinnGen and...

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Risk Factors
Sedentary Behavior
Genome-Wide Association Study
Mendelian Randomization Analysis
Pain

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sleep Initiation and Maintenance Disorders

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Identifiers

PMID: 39379490
DOI: 10.1038/s41598-024-75393-2
PMCID: PMC11461912

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