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Article

Genetic evidence for causal effects of lifestyle factors, psychiatric factors, and socioeconomic status on various spinal disorders.

Postgraduate medical journal - 20 May 2026

Shao Jiashen, Xu Shengzhe, Zhang Huixin, Meng Hai, Fei Qi

Abstract excerpt

PURPOSE: The main objective of this study was to investigate the causal association between genetic susceptibility of lifestyle, psychosocial factors, socioeconomic status, and various spinal disorders by using bidirectional Mendelian randomization (MR). MATERIALS AND METHODS: We used a bidirectional MR analysis to explore the association between 28 lifestyle, psychosocial factors, socioeconomic status, and a...

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Alcohol Drinking
Genetic Predisposition to Disease
Intervertebral Disc Degeneration
Life Style
Mendelian Randomization Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Spinal Diseases

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PMID: 41385285
DOI: 10.1093/postmj/qgaf221

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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