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Investigating the causal relationship between physical activity and chronic back pain: a bidirectional two-sample Mendelian randomization study

2021-07-22

Abstract excerpt

<h4>Background</h4> Recent observational studies have reported a negative association between physical activity and chronic back pain (CBP), but the causality of the association remains unknown. We introduce bidirectional Mendelian randomization (MR) to assess potential causal inference between physical activity and CBP. <h4>Methods</h4> The two-sample MR was used with independent genetic variants associated with...

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Literature Corpus work
336721f7-4f54-5aa7-bb21-ffc2bf4bb59d
DOI
10.1101/2021.07.20.21260847
Open publication

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Investigating the causal relationship between physical activity and chronic back pain: a bidirectional two-sample Mendelian randomization studyDOI 10.1101/2021.07.20.21260847
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