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Article

Prevalence of ten LRRK2 variants in Parkinson's disease: A comprehensive review.

Parkinsonism & related disorders - 1 May 2022

Simpson Christopher, Vinikoor-Imler Lisa, Nassan Feiby L, Shirvan Julia, Lally Cathy, Dam Tien, Maserejian Nancy

Abstract excerpt

INTRODUCTION: Variants in the leucine-rich repeat kinase 2 gene (LRRK2) are risk factors for Parkinson's disease (PD), but their prevalence varies geographically, reflecting the locations of founder events and dispersion of founders' descendants. METHODS: A comprehensive literature review was conducted to identify studies providing prevalence estimates for any of ten variants in LRRK2 (G2019S, R1441C, R1441G,...

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PMID: 35654702
DOI: 10.1016/j.parkreldis.2022.05.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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