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Article

LRRK2 variation and Parkinson's disease in African Americans.

Movement disorders : official journal of the Movement Disorder Society - 15 Sept 2010

Ross Owen A, Wilhoite Greggory J, Bacon Justin A, Soto-Ortolaza Alexandra, Kachergus Jennifer, Cobb Stephanie A, Puschmann Andreas, Vilariño-Güell Carles, Farrer Matthew J, Graff-Radford Neill, Meschia James F, Wszolek Zbigniew K

Abstract excerpt

The global impact of LRRK2 mutations is yet to be realized with a lack of studies in specific ethnic groups, including those of Asian and African descent. Herein, we investigated the frequency of common LRRK2 variants by complete exon sequencing in a series of publicly available African American Parkinson's disease patients. Our study identified three novel synonymous exonic variants and 13 known coding...

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Identifiers

PMID: 20669299
DOI: 10.1002/mds.23163
PMCID: PMC2939165

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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