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Article

Shp2 in Alveolar Macrophages Regulates Macrophage I Phenotype in Acute Lung Injury.

International journal of toxicology - 1 Jan 2000

Wang Dawei, Cao Qiumei

Abstract excerpt

Macrophage play important role in acute lung injury (ALI). This study aims to explore the possible role of Shp2 in regulating macrophage 1 (M1) in ALI progression. ALI was induced in rats by intravenous injection of lipopolysacharide (LPS). Lentivirus was used to knock down Shp2 expression. Lungs from LPS-induced ALI rats were evaluated by H&E staining and wet/dry lung weight ratio (W/D ratio) measurement....

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Source

Identifiers

PMID: 35652623
DOI: 10.1177/10915818221105227

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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