Article
Macrophage Polarization: An Important Candidate Regulator for Lung Diseases.
Molecules (Basel, Switzerland) - 4 Mar 2023
Deng Lishuang, Jian Zhijie, Xu Tong, Li Fengqin, Deng Huidan, Zhou Yuancheng, Lai Siyuan, Xu Zhiwen, Zhu Ling
Abstract excerpt
Macrophages are crucial components of the immune system and play a critical role in the initial defense against pathogens. They are highly heterogeneous and plastic and can be polarized into classically activated macrophages (M1) or selectively activated macrophages (M2) in response to local microenvironments. Macrophage polarization involves the regulation of multiple signaling pathways and transcription...
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