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Article

IRF5 regulates lung macrophages M2 polarization during severe acute pancreatitis in vitro.

World journal of gastroenterology - 14 Nov 2016

Sun Kang, He Song-Bing, Qu Jian-Guo, Dang Sheng-Chun, Chen Ji-Xiang, Gong Ai-Hua, Xie Rong, Zhang Jian-Xin

Abstract excerpt

AIM: To investigate the role of interferon regulatory factor 5 (IRF5) in reversing polarization of lung macrophages during severe acute pancreatitis (SAP) in vitro. METHODS: A mouse SAP model was established by intraperitoneal (ip) injections of 20 μg/kg body weight caerulein. Pathological changes in the lung were observed by hematoxylin and eosin staining. Lung macrophages were isolated from bronchoalveolar...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27895424
DOI: 10.3748/wjg.v22.i42.9368
PMCID: PMC5107700

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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