Article

Inhibition of EZH2 prevents acute respiratory distress syndrome (ARDS)-associated pulmonary fibrosis by regulating the macrophage polarization phenotype

2020-10-13

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> We recently reported histone methyltransferase enhancer of zeste homolog 2 (EZH2) as a key epigenetic regulator that contributes to the dysfunction of innate immune responses to sepsis and subsequent lung injury by mediating the imbalance of macrophage polarization. However, the role of EZH2 in acute respiratory distress syndrome (ARDS)-associated fibrosis remai...

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Literature Corpus work: daaa7ef6-5ac3-5bee-ae53-c84afdab7502
DOI: 10.21203/rs.3.rs-91068/v1

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