Article
A Study on the Role of Wip1 in Renal Fibrosis by Modulating Macrophage Phenotype.
Archives of medical research - 1 Jun 2023
Jia Lining, Wang Yinhong, Ma Xiaotao, Wang Hao, Fu Rongguo
Abstract excerpt
BACKGROUND: Renal fibrosis is the result of chronic kidney diseases, the exploration of the pathogenesis of renal fibrosis and the development of effective treatment methods have become major challenges. AIMS: To investigate the effect of wild-type p53-induced phosphatase 1 (Wip1) on macrophage phenotype regulation and the role played in renal fibrosis. METHODS: RAW264.7 macrophages were stimulated by...
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