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Molecular Determinants Regulating the Plasticity of the MHC Class II Immunopeptidome

16 May 2022

Abstract excerpt

In the last few years, advancement in the analysis of the MHC class II (MHC-II) ligandome in several mouse and human haplotypes has increased our understanding of the molecular components that regulate the range and selection of the MHC-II presented peptides, from MHC class II molecule polymorphisms to the recognition of different conformers, functional differences in endosomal processing along the endocytic...

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PMID: 35651601
DOI: 10.3389/fimmu.2022.878271

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