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Article

Intraoperative rapid molecular diagnosis aids glioma subtyping and guides precise surgical resection.

Annals of clinical and translational neurology - 1 Aug 2024

Li Jia, Han Zhe, Ma Caizhi, Chi Huizhong, Jia Deze, Zhang Kailiang, Feng Zichao, Han Bo, Qi Mei, Li Gang, Li Xueen, Xue Hao

Abstract excerpt

OBJECTIVE: The molecular era of glioma diagnosis and treatment has arrived, and a single rapid histopathology is no longer sufficient for surgery. This study sought to present an automatic integrated gene detection system (AIGS), which enables rapid intraoperative detection of IDH/TERTp mutations. METHODS: A total of 78 patients with gliomas were included in this study. IDH/TERTp mutations were detected...

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Identifiers

PMID: 38924338
DOI: 10.1002/acn3.52138
PMCID: PMC11330232

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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