Article
Intraoperative Mass Spectrometry Platform for IDH Mutation Status Prediction, Glioma Diagnosis, and Estimation of Tumor Cell Infiltration.
The journal of applied laboratory medicine - 7 Jul 2021
Brown Hannah Marie, Alfaro Clint M, Pirro Valentina, Dey Mahua, Hattab Eyas M, Cohen-Gadol Aaron A, Cooks R Graham
Abstract excerpt
BACKGROUND: Surgical tumor resection is the primary treatment option for diffuse glioma, the most common malignant brain cancer. The intraoperative diagnosis of gliomas from tumor core samples can be improved by use of molecular diagnostics. Further, residual tumor at surgical margins is a primary cause of tumor recurrence and malignant progression. This study evaluates a desorption electrospray ionization mass...
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