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[Propagation and phenotypic analysis of mutant rabbits with MSTN homozygous mutation].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology - 25 May 2022

Shang Liqing, Song Shaozheng, Zhang Ting, Yan Kunning, Cai Heqing, Yuan Yuguo, Cheng Yong

Abstract excerpt

Myostatin gene (MSTN) encodes a negative regulator for controlling skeletal muscle growth in animals. In this study, MSTN-/- homozygous mutants with "double muscle" phenotypic traits and stable inheritance were bred on the basis of MSTN gene editing rabbits, with the aim to establish a method for breeding homozygous progeny from primary MSTN biallelic mutant rabbits. MSTN-/- primary mutant rabbits were generated...

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Identifiers

PMID: 35611733
DOI: 10.13345/j.cjb.210541

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