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Association of the top 20 Alzheimer's disease risk genes with [18F]flortaucipir PET

1 Jan 2022

Abstract excerpt

Abstract Introduction We previously reported genetic associations of the top Alzheimer's disease (AD) risk alleles with amyloid deposition and neurodegeneration. Here, we report the association of these variants with [18F]flortaucipir standardized uptake value ratio (SUVR). Methods We analyzed the [18F]flortaucipir scans of 352 cognitively normal (CN), 160 mild cognitive impairment (MCI), and 54 dementia (DEM)...

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PMID: 35592828
DOI: 10.1002/dad2.12308

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