Article
MRI and flortaucipir relationships in Alzheimer's phenotypes are heterogeneous.
Annals of clinical and translational neurology - 1 May 2020
Josephs Keith A, Tosakulwong Nirubol, Graff-Radford Jonathan, Weigand Stephen D, Buciuc Marina, Machulda Mary M, Jones David T, Schwarz Christopher G, Senjem Matthew L, Ertekin-Taner Nilufer, Kantarci Kejal, Boeve Bradley F, Knopman David S, Jack Clifford R, Petersen Ronald C, Lowe Val J, Whitwell Jennifer L
Abstract excerpt
OBJECTIVE: To assess the relationships between MRI volumetry and [18 F]flortaucipir PET of typical and atypical clinical phenotypes of Alzheimer's disease, by genarian (age by decade). METHODS: Five-hundred and sixty-four participants including those with typical (n = 86) or atypical (n = 80) Alzheimer's dementia and normal controls (n = 398) underwent apolipoprotein E genotyping, MRI, flortaucipir, and 11 C-PiB;...
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