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Brain Epitranscriptomic Analysis Revealed Altered A-to-I RNA Editing in Septic Patients

26 Apr 2022

Abstract excerpt

Recent studies suggest that RNA editing is associated with impaired brain function and neurological and psychiatric disorders. However, the role of A-to-I RNA editing during sepsis-associated encephalopathy (SAE) remains unclear. In this study, we analyzed adenosine-to-inosine (A-to-I) RNA editing in postmortem brain tissues from septic patients and controls. A total of 3024 high-confidence A-to-I RNA editing...

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PMID: 35559016
DOI: 10.3389/fgene.2022.887001

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