Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Carbamazepine-modified HLA-A*24:02-bound peptidome: Implication of CORO1A in skin rash.

International immunopharmacology - 1 Aug 2022

Min Fuli, Fan Cuixia, Zeng Yuanjin, He Na, Zeng Tao, Qin Bing, Shi Yiwu

Abstract excerpt

BACKGROUND: Previous studies have demonstrated that human leukocyte antigen (HLA)-A*24:02 is a common genetic risk factor for antiepileptic drug-induced skin rash, while HLA-B*15:02 is a specific risk factor for carbamazepine (CBZ)-induced Stevens Johnson syndrome and toxin epidermal necrolysis. The HLA-B*15:02 allele can alter the repertoire of endogenous peptides to trigger CBZ-induced hypersensitivity....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anticonvulsants
Share to Carbamazepine
Share to Drug Hypersensitivity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Exanthema

Share to HLA-A24 Antigen

Share to HLA-B15 Antigen

Share to Microfilament Proteins

Share to Stevens-Johnson Syndrome

Source

Identifiers

PMID: 35526384
DOI: 10.1016/j.intimp.2022.108804

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Carbamazepine-modified HLA-A*24:02-bound peptidome: Implication of CORO1A in skin rash.PMID 35526384Read ↗

Characterization of Drug-Specific CD4+ T-Cells Reveals Possible Roles of HLA Class II in the Pathogenesis of Carbamazepine Hypersensitivity ReactionsSemantic proximity Read ↗

Associations of HLA genetic variants with carbamazepine-induced cutaneous adverse drug reactions: An updated meta-analysis.Semantic proximity Read ↗

The risk of cutaneous adverse reactions among patients with the <i>HLA-A* 31:01</i> allele who are given carbamazepine, oxcarbazepine or eslicarbazepine: a perspective reviewSemantic proximity Read ↗

Unraveling the genetic link: an umbrella review on HLA-B*15:02 and antiepileptic drug-induced Stevens-Johnson syndrome/toxic epidermal necrolysis.Semantic proximity Read ↗

Genetic associations of human leukocyte antigen alleles in cutaneous delayed drug hypersensitivity reactions: An updated reviewSemantic proximity Read ↗

A Recent Update of Pharmacogenomics in Drug-induced Severe Skin ReactionsSemantic proximity Read ↗

HLA-restricted Biology of Severe Cutaneous Adverse Reactions (SCARs): Dapsone-induced Hypersensitivity as an ExampleSemantic proximity Read ↗

Drug Induced Hypersensitivity and the HLA ComplexSemantic proximity Read ↗

Genome-wide association study identifies HLA-A*3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in Japanese population.Semantic proximity Read ↗

Genetic variants associated with severe cutaneous adverse drug reactions induced by carbamazepine.Semantic proximity Read ↗

Shared and restricted T-cell receptor use is crucial for carbamazepine-induced Stevens-Johnson syndrome.Semantic proximity Read ↗

HLA-A*3101 and carbamazepine-induced hypersensitivity reactions in Europeans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.