The risk of cutaneous adverse reactions among patients with the <i>HLA-A* 31:01</i> allele who are given carbamazepine, oxcarbazepine or eslicarbazepine: a perspective review

Abstract excerpt

Carbamazepine is a drug that is widely used for the treatment of epilepsy, trigeminal neuralgia and bipolar disorder. This drug is also known to cause cutaneous adverse drug reactions (cADRs) in up to 10% of patients. The recent progress in pharmacogenetics has revealed that human leukocyte antigen (HLA) genotypes are associated with a susceptibility to the cADRs caused by particular drugs. For...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Autoimmune Bullous Skin Diseases
• Share to Drug-Induced Adverse Reactions
• Share to Mast cells and histamine