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Article

Characterization of Plasma Extrachromosomal Circular DNA in Gouty Arthritis

6 Apr 2022

Abstract excerpt

Objective: Extrachromosomal circular DNA elements (eccDNAs) are known for their broad existence in cells and plasma, which may potentially play important roles in many biological processes. Our aim was to identify potentially functional or marked eccDNAs in gout patients. Methods: The Circle-Seq approach was applied for eccDNA detection from plasma in acute gout patients and healthy controls. Further analysis was...

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PMID: 35464862
DOI: 10.3389/fgene.2022.859513

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