Article
Cell free extrachromosomal circular DNA is common in human urine
2021-12-05
Abstract excerpt
Cell free extrachromosomal circular DNA (eccDNA) is evolving as a potential biomarker in liquid biopsies for disease diagnosis. In this study, an optimized next generation sequencing-based Circle-Seq method was developed to investigate urinary cell free eccDNA (ucf-eccDNA) from 28 adult healthy volunteers (mean age = 28, 19 males/ 9 females). The genomic distributions and sequence compositions of ucf-eccDNAs were...
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Identifiers and source
- Literature Corpus work
- 2fe91c08-39ec-5443-9a95-21b2fcfe45f6
- DOI
- 10.1101/2021.12.02.471038