Article
Schizophrenia and Bipolar Polygenic Risk Scores in Relation to Intracranial Volume.
Genes - 14 Apr 2022
de Zwarte Sonja M C, Brouwer Rachel M, Kahn René S, van Haren Neeltje E M
Abstract excerpt
Schizophrenia and bipolar disorder are neurodevelopmental disorders with overlapping symptoms and a shared genetic background. Deviations in intracranial volume (ICV)—a marker for neurodevelopment—differ between schizophrenia and bipolar disorder. Here, we investigated whether genetic risk for schizophrenia and bipolar disorder is related to ICV in the general population by using the UK Biobank data (n = 20,196)....
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