Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Shared genetic architecture of gray matter deficits in schizophrenia and bipolar disorder: evidence from structural neuroimaging-genetic analyses.

Psychological medicine - 14 May 2026

Xie Yingying, Du Jiaojiao, Jiang Yurong, Zhao Yao, Lin Shiqi, Zhu Wenshuang, Cao Dairong

Abstract excerpt

BACKGROUND: Schizophrenia (SCZ) and bipolar disorder (BD) share substantial clinical and neuroanatomical features, yet the neurogenetic basis underlying their shared gray matter volume (GMV) deficits remains poorly understood. METHODS: We conducted meta-analyses to identify convergent GMV alterations across the two disorders. Genome-wide association studies (GWAS) were performed to uncover genetic variants...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bipolar Disorder
Share to Genetic Risk Score

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Gray Matter

Share to Magnetic Resonance Imaging

Share to Neuroimaging

Share to Polymorphism, Single Nucleotide

Share to Schizophrenia

Source

Open in PubMed Open full text

Identifiers

PMID: 42130287
DOI: 10.1017/S0033291726104334
PMCID: PMC13200159

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Shared genetic architecture of gray matter deficits in schizophrenia and bipolar disorder: evidence from structural neuroimaging-genetic analyses.PMID 42130287Read ↗

Schizophrenia and Bipolar Polygenic Risk Scores in Relation to Intracranial Volume.Semantic proximity Read ↗

Partitioning heritability analysis reveals a shared genetic basis of brain anatomy and schizophrenia.Semantic proximity Read ↗

Associated genetics and connectomic circuitry in schizophrenia and bipolar disorderSemantic proximity Read ↗

Brain Heterogeneity in Schizophrenia and Its Association With Polygenic RiskSemantic proximity Read ↗

Associated Genetics and Connectomic Circuitry in Schizophrenia and Bipolar Disorder.Semantic proximity Read ↗

Shared Genetic Risk of Schizophrenia and Gray Matter Reduction in 6p22.1.Semantic proximity Read ↗

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes.Semantic proximity Read ↗

Association of genetic risks for schizophrenia and bipolar disorder with specific and generic brain structural endophenotypes.Semantic proximity Read ↗

Schizophrenia risk variants modulate white matter volume across the psychosis spectrum: evidence from two independent cohorts.Semantic proximity Read ↗

Multi-scale analysis of schizophrenia risk genes, brain structure, and clinical symptoms reveals integrative clues for subtyping schizophrenia patientsSemantic proximity Read ↗

Network localization of genetic risk for schizophrenia and bipolar disorder.Semantic proximity Read ↗

Brain structural correlates of familial risk for mental illness: a meta-analysis of voxel-based morphometry studies in relatives of patients with psychotic or mood disorders.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.