Article
Pancreatic Ductal Carcinoma Risk Associated With Hereditary Cancer-Risk Genes.
Journal of the National Cancer Institute - 11 Jul 2022
Gardiner Anna, Kidd John, Elias Maria C, Young Kayla, Mabey Brent, Taherian Nassim, Cummings Shelly, Malafa Mokenge, Rosenthal Eric, Permuth Jennifer B
Abstract excerpt
BACKGROUND: Although several hereditary cancer predisposition genes have been implicated in pancreatic ductal adenocarcinoma (PDAC) susceptibility, gene-specific risks are not well defined and are potentially biased because of the design of previous studies. More precise and unbiased risk estimates can result in screening and prevention better tailored to genetic findings. METHODS: This is a retrospective...
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