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Article

Understanding familial risk of pancreatic ductal adenocarcinoma.

Familial cancer - 1 Nov 2024

Paranal Raymond M, Wood Laura D, Klein Alison P, Roberts Nicholas J

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease that is the result of an accumulation of sequential genetic alterations. These genetic alterations can either be inherited, such as pathogenic germline variants that are associated with an increased risk of cancer, or acquired, such as somatic mutations that occur during the lifetime of an individual. Understanding the genetic basis of inherited risk of...

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Identifiers

PMID: 38609521
DOI: 10.1007/s10689-024-00383-2
PMCID: PMC11660179

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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