Article
Identification of high-risk germline variants for the development of pancreatic cancer: Common characteristics and potential guidance to screening guidelines.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] - 1 Sept 2022
Bennett Cade, Suguitan Mike, Abad John, Chawla Akhil
Abstract excerpt
Pancreatic cancer (PC) is a product of a variety of environmental and genetic factors. Recent work has highlighted the influence of hereditary syndromes on pancreatic cancer incidence. The purpose of this review is to identify the high-risk syndromes, common variants, and risks associated with PC. The study also elucidates common characteristics of patients with these mutations, which is used to recommend...
Topics
- Early Detection of Cancer
- Genetic Predisposition to Disease
- Germ Cells
- Germ-Line Mutation
- Humans
- Pancreatic Neoplasms
- Syndrome
- Trypsin Inhibitor, Kazal Pancreatic