Article
Inherited predisposition to pancreatic cancer.
Seminars in oncology - 1 Feb 2021
Hilfrank Kimberly J, Rustgi Sheila D, Kastrinos Fay
Abstract excerpt
Pancreatic ductal adenocarcinoma (PDAC) is projected to be the second leading cause of cancer death in the US by 2030. There are multiple germline pathogenic variants and cancer syndromes associated with an increased risk of PDAC. Precision treatment, informed by germline genetic testing and molecular tumor analysis, can optimize therapeutic regimens and outcomes for those diagnosed with PDAC. As a result, the...
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