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Article

Prevalence of Pathogenic Mutations in Cancer Predisposition Genes among Pancreatic Cancer Patients.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jan 2016

Hu Chunling, Hart Steven N, Bamlet William R, Moore Raymond M, Nandakumar Kannabiran, Eckloff Bruce W, Lee Yean K, Petersen Gloria M, McWilliams Robert R, Couch Fergus J

Abstract excerpt

The prevalence of germline pathogenic mutations in a comprehensive panel of cancer predisposition genes is not well-defined for patients with pancreatic ductal adenocarcinoma (PDAC). To estimate the frequency of mutations in a panel of 22 cancer predisposition genes, 96 patients unselected for a family history of cancer who were recruited to the Mayo Clinic Pancreatic Cancer patient registry over a 12-month...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26483394
DOI: 10.1158/1055-9965.EPI-15-0455
PMCID: PMC4754121

Genes

ATM
BARD1
BRCA1
BRCA2
CHEK2
FANCM
MSH6
NBN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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