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p53 at the crossroad of DNA replication and ribosome biogenesis stress pathways

20 Apr 2022

Abstract excerpt

Despite several decades of intense research focused on understanding function(s) and disease-associated malfunction of p53, there is no sign of any "mid-life crisis" in this rapidly advancing area of biomedicine. Firmly established as the hub of cellular stress responses and tumor suppressor targeted in most malignancies, p53's many talents continue to surprise us, providing not only fresh insights into cell and...

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PMID: 35444234
DOI: 10.1038/s41418-022-00999-w

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