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p53 and ribosome biogenesis stress: The essentials

18 Apr 2014

Abstract excerpt

Cell proliferation and cell growth are two tightly linked processes, as the proliferation program cannot be executed without proper accumulation of cell mass, otherwise endangering the fate of the two daughter cells. It is therefore not surprising that ribosome biogenesis, a key element in cell growth, is regulated by many cell cycle regulators. This regulation is exerted transcriptionally and...

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PMID: 24747423
DOI: 10.1016/j.febslet.2014.04.014

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