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Battle Against Cancer: An Everlasting Saga of p53

1 Dec 2014

Abstract excerpt

Cancer is one of the most life-threatening diseases characterized by uncontrolled growth and spread of malignant cells. The tumor suppressor p53 is the master regulator of tumor cell growth and proliferation. In response to various stress signals, p53 can be activated and transcriptionally induces a myriad of target genes, including both protein-encoding and non-coding genes, controlling cell cycle progression,...

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PMID: 25470027
DOI: 10.3390/ijms151222109

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