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Article

Genetics of methamphetamine use disorder: A systematic review and meta-analyses of gene association studies.

Neuroscience and biobehavioral reviews - 1 Jan 2021

Guerin Alexandre A, Nestler Eric J, Berk Michael, Lawrence Andrew J, Rossell Susan L, Kim Jee Hyun

Abstract excerpt

Genetic susceptibility to methamphetamine use disorder is poorly understood. No twin or adequately powered genome-wide association studies (GWASs) have been conducted. However, there are a large number of hypothesis-driven candidate gene association studies, which were systematically reviewed herein. Seventy-six studies were identified, investigating markers of 75 different genes. Allele frequencies, odds ratios,...

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Amphetamine-Related Disorders
Brain-Derived Neurotrophic Factor
Genetic Association Studies
Genetic Predisposition to Disease
Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Methamphetamine

Polymorphism, Single Nucleotide

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Identifiers

PMID: 33217458
DOI: 10.1016/j.neubiorev.2020.11.001
PMCID: PMC7856253

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