Article
CDKN1A and CDKN1B polymorphisms and risk of advanced prostate carcinoma.
Cancer research - 1 May 2003
Kibel Adam S, Suarez Brian K, Belani Jay, Oh Joe, Webster Raul, Brophy-Ebbers Michele, Guo Chan, Catalona William J, Picus Joel, Goodfellow Paul J
Abstract excerpt
A multigenic model of prostate cancer susceptibility has been proposed, in which common polymorphic variants of genes, such as the androgen and vitamin D receptor, contribute to tumorigenesis. The discovery of additional genetic factors that contribute to prostate cancer risk should provide opportunities for new approaches to the detection and treatment of this common malignancy. Herein, we examined single...
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