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Article

Are cell cycle and apoptosis genes associated with prostate cancer risk in North Indian population?

Urologic oncology - 1 Sept 2012

Mandal Raju Kumar, Mittal Rama Devi

Abstract excerpt

OBJECTIVE: Prostate cancer (CaP) is a heterogeneous, multifactorial, and multifocal disease. Therefore, the search for a combination of functional polymorphisms using cell cycle and apoptotic genes as tumor markers is fundamental for a more precise and reliable diagnosis. In the present study, we investigated the diagnostic value of 3 different genes associated with CaP carcinogenesis, encoding for cell cycle...

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PMID: 20822933
DOI: 10.1016/j.urolonc.2010.05.006

Genes

CCND1
MDM2

Variants

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