Article
[Single nucleotide polymorphisms of CYP1A2 and their correlation with prostate cancer].
Zhonghua nan ke xue = National journal of andrology - 1 Nov 2011
Wei Wu, Ge Jing-ping, Dong Jie, Gao Jian-ping, Zhang Zheng-yu, Gong Jun
Abstract excerpt
OBJECTIVE: To evaluate the correlation of the single nucleotide polymorphisms (SNPs) of the CYP1A2 gene with the stages and grades of prostate cancer (PCa). METHODS: We conducted gene sequencing of the rs2069514-3859 (A > G) and rs2069525-1707 (C >T) alleles in the CYP1A2 gene in 253 patients with benign prostatic hyperplasia (BPH) and 206 patients with PCa treated by castration therapy, and statistically...
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