Article
Effect of the CCND1 A870G polymorphism on prostate cancer risk: a meta-analysis of 3,820 cases and 3,825 controls.
World journal of surgical oncology - 15 Feb 2015
Zheng Min, Wan Lijun, He Xiang, Qi Xiaolong, Liu Feng, Zhang Da-Hong
Abstract excerpt
BACKGROUND: Cyclin D1 (CCND1) is critical in the transition of the cell cycle from the G1 to S phases, and unbalanced cell cycle regulation is a hallmark of carcinogenesis. Numerous epidemiological studies have evaluated the association between the CCND1 A870G polymorphism and the risk of prostate cancer (PCa). However, these studies have yielded conflicting results. METHODS: In the present study, the possible...
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