Article

Meta-Analysis of Transcriptome-Wide Association Studies Across 13 Brain Tissues Identified Novel Clusters of Genes Associated with Nicotine Addiction

2021-11-22

Abstract excerpt

Genome-wide association studies (GWAS) have identified and reproduced thousands of diseases associated loci but many of them are not directly interpretable due to the strong linkage disequilibrium among variants. Transcriptome-wide association studies (TWAS) incorporated expression quantitative trait loci (eQTL) cohorts as reference panel to detect associations with the phenotype at the gene level and were gaining...

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Literature Corpus work: a467730c-8e5c-57cc-a42c-59ce3e0610f5
DOI: 10.20944/preprints202111.0386.v1

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