Article
Mendelian randomization study of diabetes, blood lipids, and the risk of knee and hip osteoarthritis.
Advances in clinical and experimental medicine : official organ Wroclaw Medical University - 1 Mar 2026
Dong Peilong, Zhu Botao, Li Zhiyun, Tang Xiaobo
Abstract excerpt
BACKGROUND: Osteoarthritis (OA), particularly knee and hip osteoarthritis (KOA and HOA), is a leading cause of disability. Although diabetes-related factors and lipid abnormalities have been implicated in OA development, the causal nature of these associations remains unclear. OBJECTIVES: This study investigates the relationships between diabetes-related factors (type 2 diabetes (T2D), fasting insulin and...
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