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Article

The Causal Effects Between Circulating Inflammatory Proteins and Osteoarthritis: A Mendelian Randomization and Transcriptomic Analysis

1 Jul 2025

Abstract excerpt

Background: Observational studies have demonstrated the correlation between various inflammatory proteins and osteoarthritis (OA). However, the causal relationship and directionality between them are still unclear. This study aims to analyze the potential causal relationship between circulating inflammatory proteins and OA using Mendelian randomization (MR) analysis. Methods: This study used bidirectional...

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PMID: 40630929
DOI: 10.2147/jpr.s523677

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