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Article

Effect of drug combination on tacrolimus target dose in renal transplant patients with different CYP3A5 genotypes.

Xenobiotica; the fate of foreign compounds in biological systems - 1 Mar 2022

Zhang Shu-Fang, Tang Bo-Hao, Wei An-Hua, Du Yue, Guan Zi-Wan, Li Yan

Abstract excerpt

Various factors, including genetic polymorphisms, drug-drug interactions, and patient characteristics influence the blood concentrations of tacrolimus in renal transplant patients. In the present study, we established a population pharmacokinetic model to explore the effect of combined use of Wuzhi capsules/echinocandins and the patients' biochemical parameters such as haematocrit on blood concentrations and...

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Identifiers

PMID: 35395919
DOI: 10.1080/00498254.2022.2064252

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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