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Beneficial effects of traditional Chinese medicine Wuzhi Capsule on tacrolimus dose requirements in liver transplant patients with different donor-recipient CYP3A5 genotypes

2021-03-19

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<title>Abstract</title> <p><bold>Background/Aims: </bold>Tacrolimus (Tac) is an immunosuppressant that is widely used to prevent allograft rejection in patients after liver transplantation. Recently, a Chinese herbal medicine known as Wuzhi Capsule (WZC) was shown to increase Tac blood concentrations by inhibiting the activity of CYP3A5 in animal studies in rats. To date, it remains unexplored whether WZC can be...

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Literature Corpus work
39b1f0a7-95b0-5798-91c1-db8644f7ae56
DOI
10.21203/rs.3.rs-325961/v1
Open publication

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Beneficial effects of traditional Chinese medicine Wuzhi Capsule on tacrolimus dose requirements in liver transplant patients with different donor-recipient CYP3A5 genotypesDOI 10.21203/rs.3.rs-325961/v1
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