Article
Prediction of tacrolimus and Wuzhi tablet pharmacokinetic interaction magnitude in renal transplant recipients.
Clinical transplantation - 1 Dec 2022
Chen Pan, Dai Rui, She Youjun, Fu Qian, Huang Min, Chen Xiao, Wang Changxi
Abstract excerpt
AIM: Wuzhi tablets are a dose-sparing agent for tacrolimus (TAC) in China and increase the bioavailability of TAC. The current study aimed to evaluate the pharmacokinetic interaction magnitude of Wuzhi and TAC and explore the potential determinants of this interaction. METHODS: This study performed a retrospective, self-controlled study of 138 renal transplant recipients who were co-administered TAC and Wuzhi....
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