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Article

Development and validation of polygenic risk scores for prediction of breast cancer and breast cancer subtypes in Chinese women.

BMC cancer - 8 Apr 2022

Hou Can, Xu Bin, Hao Yu, Yang Daowen, Song Huan, Li Jiayuan

Abstract excerpt

BACKGROUND: Studies investigating breast cancer polygenic risk score (PRS) in Chinese women are scarce. The objectives of this study were to develop and validate PRSs that could be used to stratify risk for overall and subtype-specific breast cancer in Chinese women, and to evaluate the performance of a newly proposed Artificial Neural Network (ANN) based approach for PRS construction. METHODS: The PRSs were...

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Identifiers

PMID: 35395775
DOI: 10.1186/s12885-022-09425-3
PMCID: PMC8991589

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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